Generation of patient-specific pluripotent stem cells and directed differentiation of embryonic stem cells for regenerative medicine
Minyue Ma
Jiahao Sha
Zuomin Zhou
Qi Zhou
Qingzhang Li
摘要：Embryonic stem(ES) cells are pluripotent cells that can give rise to derivatives of all three embryonic germ layers. Due to its characteristics, the patient-specific ES cells are of great potential for transplantation therapies. Several strategies can reprogramme somatic cells back to pluripotent stem cells: nuclear transfer, fusion with ES cells, treatment with cell extract and induction by specific factors. Considering the future clinical use, the differentiation from ES to neurons, cardiomyocytes and many other types of cell scurrently provide basic cognition and experience to regenerative medicine. This article will review two courses, the reprogramming of differentiated cells and the differentiation of ES cells to specific cell types.
机标关键词：
分类号：R9(药学)
论文发表日期：2008-05-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：8( 135-142 )
英文信息