Immunomodulation effects of heat-treated Enterococcus faecalis FK-23(FK-23) in mice
Takashi Shimada
Yunqing Cai
Lei Cheng
Chie Motonaga
Kazutake Fukada
Yoshihisa Kitamura
Jieshu Wu
摘要:Objective:The purpose of this study was to evaluate the effects of Enterococcus faecalis FK-23(FK-23) on the immune function in mice. Methods:Mice were treated with three doses of the FK-23(0.05, 0.1, 0.2, 0.6 g/kg body weight) for 30 days. Delayed type hypersensitivity (DTH), monocyte phagocytic function, serum hemolysis antibody and natural killer cell activity were studied. Results: The significant increases in mice treated with 0.6 g/kg bw were found in DTH, phagocytic function of monocyte, serum hemolysis antibody and natural killer cell activity. Conclusion:The results from the present study suggest that FK-23 could improve both specific and nonspecific immune function.
机标关键词:phagocytic functionnatural killer cellimmune functionDelayed type hypersensitivitytreatedResultsMicesignificant
分类号:R5(内科学)
论文发表日期:2009-01-01
在线出版日期:2025-08-15(本平台首次上网日期,不代表文献的发表时间)
页数:4( 173-176 )
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南京医科大学学报(英文版)

南京医科大学学报(英文版)

ISSN:1007-4376
年,卷(期):2009,23(3)
所属栏目:Research Paper