Role of remote sensing, geographic bioinformatics system and bioinformatics in kala-azar epidemiology
Gouri Sankar Bhunia
Manas Ranjan Dikhit
Shreekant Kesari
Ganesh Chandra Sahoo
Pradeep Das
摘要：Visceral leishmaniasis or kala-azar is a potent parasitic infection causing death of thousands of people each year.Medicinal compounds currently available for the treatment of kala-azar have serious side effects and decreased efficacy owing to the emergence of resistant strains.The type of immune reaction is also to be considered in patients infected with Leishmania donovani (L donovani).For complete eradication of this disease,a high level modem research is currently being applied both at the molecular level as well as at the field level.The computational approaches like remote sensing,geographic information system (GIS) and bioinformatics are the key resources for the detection and distribution of vectors,patterns,ecological and environmental factors and genomic and proteomic analysis.Novel approaches like GIS and bioinformatics have been more appropriately utilized in determining the cause of visearal leishmaniasis and in designing strategies for preventing the disease from spreading from one region to another.
机标关键词：environmental factorsLeishmania donovaniinformation systemlevelimmune reactionremote sensingside effectsstrategies
分类号：R531.6(寄生虫病)R181.3(流行病学与防疫)
论文发表日期：2011-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
英文信息