Active motif finder - a bio-tool based on mutational structures in DNA sequences
Mani Udayakumar
Palaniyandi Shanmuga-priya
Kamalakannan Hemavathi
Rengasamy Seenivasagam
摘要：Active Motif Finder (AMF) is a novel algorithmic tool,designed based on mutations in DNA sequences.Tools available at present for finding motifs are based on matching a given motif in the query sequence.AMF describes a new algorithm that identifies the occurrences of patterns which possess all kinds of mutations like insertion,deletion and mismatch.The algorithm is mainly based on the Alignment Score Matrix (ASM) computation by comparing input motif with full length sequence.Much of the effort in bioinformatics is directed to identify these motifs in the sequences of newly discovered genes.The proposed bio-tool serves as an open resource for analysis and useful for studying polymorphisms in DNA sequences.AMF can be searched via a user-friendly interface.This tool is intended to serve the scientific community working in the areas of chemical and structural biology,and is freely available to all users,at
机标关键词：DNA sequencesstructuresbasedmotifMotifnew algorithmAMFAlignment
分类号：Q523(核酸)
论文发表日期：2011-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
英文信息