HLA antigens and anti-sperm antibody production in Iranian vasectomized men
Dr.Gholamreza Azizi
Dr.Saeed Namaki
Abbas Mirshafiey
Kabir Magaji Hamid
摘要：Dear Editor:
Anti-sperm antibodies (ASAs) are composed of numerous antibodies interacting with multiple sperm antigens that play a role in fertility.In males,ASAs cause ‘immune infertility’ by decreasing sperm counts and normal forms,as well as reducing sperm motility and viability,markedly reducing the likelihood of natural conception[1].The development of ASA in the male depends on the release of sequestered antigens on germ cells following the disruption of the blood-testis barrier.A surgical operation such as a vasectomy could also lead to immunogenic sperm antigens being exposed to the immune system,thus initiating an immune response to produce ASAs[2].
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论文发表日期：2015-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）