Postprandial hyperglycemia and postprandial hypertriglyceridemia in type 2 diabetes
Tom Hiyoshi
Mutsunori Fujiwara
Zemin Yao
摘要:Postprandial glucose level is an independent risk factor for cardiovascular disease that exerts effects greater than glucose levels at fasting state,whereas increase in serum triglyceride level,under both fasting and postprandial conditions,contributes to the development of arteriosclerosis.Insulin resistance is a prevailing cause of abnormalities in postabsorptive excursion of blood glucose and postprandial lipid profile.Excess fat deposition renders a vicious cycle of hyperglycemia and hypertriglyceridemia in the postprandial state,and both of which are contributors to atherosclerotic change of vessels especially in patients with type 2 diabetes mellitus.Several therapeutic approaches for ameliorating each of these abnormalities have been attempted,including various antidiabetic agents or new compounds targeting lipid metabolism.
机标关键词:
分类号:R587(内分泌腺疾病及代谢病)
论文发表日期:2019-01-01
在线出版日期:2025-08-15(本平台首次上网日期,不代表文献的发表时间)
页数:16( 1-16 )
英文信息
