Association between Pri-miR-34b/c rs4938723 polymorphism and bladder cancer risk
Mohammad Hashemi
Vahed Hasanpour
Hiva Danesh
Fatemeh Bizhani
Behzad Narouie
摘要：Several studies examined the impact ofmiR-34b/c rs4938723 polymorphism and cancer risk,but the findings are inconsistent.However,no study has been conducted to inspect the impact of miR-34b/c polymorphism on bladder cancer.This study aimed to assess possible association between rs4938723 polymorphism and bladder cancer risk.This case-control study was done on 136 pathologically proven bladder cancer patients and 144 controls.Genotyping of Pri-miR-34b/c rs4938723 polymorphism was achieved by using the polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) method.Our findings did not show any statistically significant differences in genotype and allele frequencies between bladder cancer and controls.Larger sample sizes with diverse ethnicities are required to validate our findings.
机标关键词：
分类号：R737.14(泌尿生殖器肿瘤)
资助基金：This paper was funded by a research grant (#8067)
论文发表日期：2019-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：6( 24-29 )
英文信息