The level of bile salt-stimulated lipase in the milk of Chinese women and its association with maternal BMI
Lijun Sha
Shanshan Zhou
Yangyang Xi
Rong Li
Xiaonan Li
1.Department of Children Health Care, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu 210008,China2.Department of Children Health Care, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu 210008,China3.Department of Children Health Care, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu 210008,China4.Department of Children Health Care, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu 210008,China5.Department of Children Health Care, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu 210008,China
摘要：This study aimed to investigate the bile salt-stimulated lipase (BSSL) concentration in the milk of Chinese women and its correlation with maternal body mass index (BMI),gestational diabetes mellitus (GDM) and gestational hypertensive disorder (GHD).The BSSL levels in the milk samples were measured by enzyme-linked immunosorbent assay (ELISA).BSSL level in colostrum milk of mothers with full-term infants was positively correlated with pregnancy week and negatively correlated with maternal pre-pregnancy BMI and BMI late in pregnancy.Moreover,the BSSL concentration in mature milk was positively correlated with BMI gain during pregnancy.The BSSL concentration in colostrum milk was lower in GDM mothers than in normal mothers.The BSSL helps infants digest fat in early life and its level was associated with lactation.The changes in BSSL characteristics with maternal BMI and GDM in this study may have clinical implications regarding the effects of pregnancy weight and metabolism on the nutrition and health of the offspring.
机标关键词：
分类号：R174(妇幼卫生)
论文发表日期：2020-03-30
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：7( 122-128 )
英文信息