Angiosarcomatous component in gliosarcoma: case report and consideration of diagnostic challenge and hemorrhagic propensity
Nancy Jiang1
Ramiro Larrazabal1
Waleed Alsunbul2
Jian-Qiang Lu3
1.Department of Radiology, McMaster University/Hamilton Health Sciences, Hamilton, Ontario L8L 2X2, Canada2.Department of Surgery/Neurosurgery, McMaster University/Hamilton Health Sciences, Hamilton, Ontario L8L 2X2, Canada3.Department of Pathology and Molecular Medicine/Neuropathology, McMaster University/Hamilton Health Sciences, Hamilton, Ontario L8L 2X2, Canada
摘要：An angiosarcomatous component in gliosarcoma may be associated with an increased intraoperative hemorrhagic risk and preoperative diagnostic challenge.We report a unique case of gliosarcoma with an angiosarcomatous component in a 61-year-old man.His brain MRI demonstrated a well-demarcated right occipital tumor with multiple flow voids and rim-like enhancement as well as intratumoral strip and nodular enhancements.He underwent a craniotomy for tumor resection.Intraoperatively,significant tumor hemorrhage required greater efforts to control intraoperative bleeding and to maintain hemostasis.Pathological examination of the tumor revealed alternating gliomatous and sarcomatous/angiosarcomatous components with intratumoral hemorrhage.He was postoperatively treated with chemoradiation.The tumor recurred at 9 months,for which the second resection was performed with similarly greater efforts to achieve hemostasis.The recurrent tumor was pathologically similar despite treatment-associated changes.Awareness of this angiosarcomatous component in gliosarcoma with the hemorrhagic risk is important for both the preoperative diagnosis and surgical management.
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分类号：R739.41(神经系肿瘤)
论文发表日期：2020-03-30
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：6( 143-148 )
英文信息