The prognosis and short-term efficacy of corticosteroid therapy for COVID-19 patients
Xinyu Jia
Hengrui Zhang
Yuan Ma
Zhenzhen Wu
Ningfei Ji
Mao Huang
Department of Respiratory Medicine,the First Affiliated Hospital of Nanjing Medical University,Nanjing,Jiangsu 210029,China
摘要：Dear Editor:
Corticosteroids are widely used in the treatment of critically ill patients for active anti-inflammatory and immunosuppressive effects.However,the therapeutic effects of corticosteroid treatment are still disputable.Some studies have shown that corticosteroids can de-lay coronavirus RNA clearance[1],increase mortality[2]and cause adverse events[3].Conversely,other studies have confirmed the clinical value of corticosteroids in shortening hospital stays and decreasing the need for mechanical ventilation[4].Similarly,the use of corticosteroids in COVID-19 patients is controversial.Expert consensus in China has indicated that corticosteroids can be used as appropriate in critical patients[5].However,World Health Organization interim guidance opposes the routine use of corticosteroids in treatment[6].Therefore,we herein discussed the therapeutic effects of corticosteroids in COVID-19 patients based on the experience of front-line physicians and a meta-analysis.
机标关键词：
分类号：R511(传染病)
论文发表日期：2021-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：6( 247-252 )