Malnutrition predicts poor outcomes in diabetic COVID-19 patients in Huangshi,Hubei
Jiao Chen1
Can Zhao2
Yingzi Huang3
Hao Wang1
Xiang Lu2
Wei Zhao1
Wei Gao2
1.Department of Intensive Care Unit,the Affiliated Sir Run Run Hospital of Nanjing Medical University,Nanjing,Jiangsu 211100,China2.Department of Geriatrics,the Affiliated Sir Run Run Hospital of Nanjing Medical University,Nanjing,Jiangsu 211100,China;Key Laboratory for Aging&Disease,Nanjing Medical University,Nanjing,Jiangsu 211166,China3.Jiangsu Provincial Key Laboratory of Critical Care Medicine,Department of Critical Care Medicine,Zhongda Hospital,School of Medicine,Southeast University,Nanjing,Jiangsu 210009,China
摘要：Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection has spread throughout the world,which becomes a global public health emergency.Undernourishment prolongs its convalescence and has an adverse effect on its prognosis,especially in diabetic patients.The purpose of this study was to evaluate the prevalence and characteristics of undernourishment and to determine how it is related to the prognostic outcomes in the diabetic patients with coronavirus disease 2019(COVID-19).A retrospective,multicenter study was conducted in 85 diabetic COVID-19 patients from three hospitals in Hubei Province.All patients were assessed using the European Nutritional Risk Screening 2002(NRS-2002)and other nutritional assessments when admitted.Of them,35(41.18％)were at risk of malnutrition(NRS score≥3).Severe COVID-19 patients had a significantly lower level of serum albumin and prealbumin and higher NRS score than non-severe patients.Multivariate logistic regression analysis showed that serum prealbumin and NRS score increased the likelihood of progression into severe status(P＜0.05).Meanwhile,single factor and multivariate analysis determined that grade of illness severity was an independent predictor for malnutrition.Furthermore,prealbumin and NRS score could well predict severe status for COVID-19 patients.The malnutrition group(NRS score≥3)had more severe illness than the normal nutritional(NRS score＜3)group(P＜0.001),and had a longer length of in-hospital stay and higher mortality.Malnutrition is highly prevalent among COVID-19 patients with diabetes.It is associated with severely ill status and poor prognosis.Evaluation of nutritional status should be strengthened,especially the indicators of NRS-2002 and the level of serum prealbumin.
机标关键词：
分类号：R153(营养卫生、食品卫生)
论文发表日期：2022-01-30
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：7( 32-38 )
英文信息