Clinical management of primary odontogenic sarcoma in the mandible:a case report after WHO nomination
Qinghai Zhu
Chenxing Wang
Yizhou Wang
Songsong Guo
Jinhai Ye
Jiangsu Key Laboratory of Oral Diseases,Nanjing Medical University,Nanjing,Jiangsu 210029,China;Depatment of Oral and Maxillofacial Surgery,the Affiliated Stomatological Hospital of Nanjing Medical University,Nanjing,Jiangsu 210029,China
摘要：Ameloblastic fibro-odontosarcoma(AFOS)now designated as odontogenic sarcoma is an extremely rare odontogenic tumor,which histologically presents as a biphasic neoplasm with a malignant mesenchymal component plus ameloblastic epithelium.Here we report a 27-year-old Chinese female with the complaint of a painful swelling for half a month in the right mandible.A segmental mandibulectomy,with an immediate mandibular reconstruction using a free vascularized osteocutaneous fibular flap was performed using surgical guide models.Histological analysis revealed a primary odontogenic sarcoma.The postoperative period was uneventful,and no clinical indication of recurrence or metastasis was observed during the 3-year follow-up.No adjuvant therapy was proposed.This is the first odontogenic sarcoma case reported in China after the new World Health Organization classification of odontogenic lesions.
机标关键词：
分类号：R739.8(口腔、颌面部肿瘤)
论文发表日期：2022-01-30
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：5( 58-62 )
英文信息