Application of near-infrared fluorescence imaging in theranostics of gastrointestinal tumors
Nan-Qing Shi1
Xin-Yuan Cui2
Cheng Zhou1
Ning Tang1
Da-Xiang Cui3
1.Department of Sensing Science and Engineering,School of Electronic Information and Electrical Engineering,Institute of Nano Biomedicine and Engineering,Shanghai Jiao Tong University,Shanghai,P.R.China2.Department of Radiology,Ruijin Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai,P.R.China3.Department of Sensing Science and Engineering,School of Electronic Information and Electrical Engineering,Institute of Nano Biomedicine and Engineering,Shanghai Jiao Tong University,Shanghai,P.R.China;National Engineering Center for Nanotechnology,Shanghai,P.R.China
摘要：Gastrointestinal cancers have become an important cause of cancer-related death in humans.Improving the early diagnosis rate of gastrointestinal tumors and improving the effect of surgical treatment can significantly improve the survival rate of patients.The conventional diagnostic method is high-definition white-light endoscopy,which often leads to missed diagnosis.For surgical treatment,intraoperative tumor localization and post-operative anastomotic state evaluation play important roles in the effect of surgical treatment.As a new imaging method,near-infrared fluorescence imaging(NIRFI)has its unique advantages in the diagnosis and auxiliary surgical treatment of gastrointestinal tumors due to its high sensitivity and the ability to image deep tissues.In this review,we focus on the latest advances of NIRFI technology applied in early diagnosis of gastrointestinal tumors,identification of tumor margins,identification of lymph nodes,and assessment of anastomotic leakage.In addition,we summarize the advances of NIRFI systems such as macro imaging and micro imaging systems,and also clearly describe the application process of NIRFI from system to clinical application,and look into the prospect of NIRFI applied in the theranostics of gastrointestinal tumors.
机标关键词：fluorescenceapplicationimagingastrogastintestinalnear-infraredtheranostics
论文发表日期：2024-02-28
在线出版日期：2026-07-17（本平台首次上网日期，不代表文献的发表时间）
页数：12( 1-12 )
英文信息