Hirschsprung disease in an adult masquerading as stricturing Crohn's disease:a missed rare co-morbidity
Yiqian Chen1
Xiaowei Liu2
Shuijiao Chen2
1.Department of Gastroenterology,Xiangya Hospital,Central South University,Changsha,Hunan,P.R.China2.Department of Gastroenterology,Xiangya Hospital,Central South University,Changsha,Hunan,P.R.China;National Clinical Research Center for Geriatric Disorders,Xiangya Hospital,Central South University,Changsha,Hunan,P.R.China
摘要：Introduction
Hirschsprung disease(HD)is a congenital disorder of intestinal mo-tility characterized by the absence of enteric neurons at the end of the bowel[1].HD affects 1 in 5,000 live-bom infants and 90％of patients are diagnosed within the first year of life[2].Adult HD patients present with symptoms that begin in adulthood or child-hood due to failure of diagnosis[1,3].Patients with inflammatory bowel disease(IBD)are considered to be more susceptible to HD in infancy than those without IBD,with a relative risk ranging from 24 to 40 times higher[4].However,the rare co-morbidity of IBD and adult HD presenting after childhood is prone to missed diagnosis.Here,we report a case in which a patient was diagnosed with stric-turing Crohn's disease(CD)at the first visit,and pathological exam-ination after surgery revealed adult HD complicated by CD.
机标关键词：crohnadultrareco-morbiditydiseasehirschsprungmasqueradingmissed
论文发表日期：2024-02-28
在线出版日期：2026-07-17（本平台首次上网日期，不代表文献的发表时间）
页数：3( 88-90 )