Single-cell analysis for identification of T-cell clonotypes associated with IgG4 production of autoimmune pancreatitis
Kensuke Shibata1
Nao Fujimori2
Takamasa Oono2
Daisuke Motooka3
Daisuke Okuzaki3
Koh-Hei Sonoda4
Yoshihiro Ogawa2
Sho Yamasaki5
1.Department of Microbiology and Immunology,Graduate School of Medicine,Yamaguchi University,Ube,Japan;Department of Ophthalmology,Graduate School of Medical Sciences,Kyushu University,Fukuoka,Japan;Department of Molecular Immunology,Research Institute for Microbial Diseases,Osaka University,Suita,Japan2.Department of Medicine and Bioregulatory Science,Graduate School of Medical Sciences,Kyushu University,Fukuoka,Japan3.Single Cell Genomics,Human Immunology,World Premier International Research Center Initiative Immunology Frontier Research Center,Osaka University,Suita,Japan;Genome Information Research Center,Research Institute for Microbial Diseases,Osaka University,Suita,Japan4.Department of Ophthalmology,Graduate School of Medical Sciences,Kyushu University,Fukuoka,Japan5.Department of Molecular Immunology,Research Institute for Microbial Diseases,Osaka University,Suita,Japan;Laboratory of Molecular Immunology,Immunology Frontier Research Center,Osaka University,Suita,Japan;Division of Molecular Immunology,Medical Mycology Research Center,Chiba University,Chiba,Japan
摘要：Introduction
Autoimmune pancreatitis(AIP)is one of the recently established immunoglobulin G4-related diseases(IgG4-RD)[1].The detailed pathogenic mechanisms have been an intensive research area for prophylactic and therapeutic purposes because aberrant im-mune activation and tissue fibrosis in AIP are the major factors that worsen the disease outcomes in these patients.
机标关键词：identificationproductionanalysiswithassociatedautoimmuneclonotypespancreatitis
论文发表日期：2024-08-30
在线出版日期：2026-07-17（本平台首次上网日期，不代表文献的发表时间）
页数：3( 400-402 )