DOI: 10.1515/mr-2024-0030
Review of organ damage from COVID and Long COVID:a disease with a spectrum of pathology
Andrew G.Ewing1
Spela Salamon2
Etheresia Pretorius3
David Joffe4
Greta Fox2
Stephane Bilodeau5
Yaneer Bar-Yam6
1.Department of Chemistry and Molecular Biology,University of Gothenburg,Medicinareberget 7B,Gothenburg 40530,Sweden;World Health Network,Cambridge,MA 02139,USA2.World Health Network,Cambridge,MA,USA3.World Health Network,Cambridge,MA,USA;Department of Physiological Sciences,Faculty of Science,Stellenbosch University,Stellenbosch,WC,South Africa;Department of Biochemistry,Cell and Systems Biology,Institute of Systems,Molecular and Integrative Biology,Faculty of Health and Life Sciences,University of Liverpool,Liverpool,UK4.World Health Network,Cambridge,MA,USA;Faculty of Medicine and Health,The University of Sydney,Sydney,NSW,Australia5.World Health Network,Cambridge,MA,USA;Department of Bioengineering,McGill University,Montreal,QC,Canada6.World Health Network,Cambridge,MA,USA;New England Complex Systems Institute,Cambridge,MA,USA
摘要：Long COVID,as currently defined by the World Health Organization(WHO)and other authorities,is a symptomatic condition that has been shown to affect an estimated 10％-30％of non-hospitalized patients after one infection.However,COVID-19 can also cause organ damage in individuals without symptoms,who would not fall under the current definition of Long COVID.This organ damage,whether symptomatic or not,can lead to various health impacts such as heart attacks and strokes.Given these observations,it is necessary to either expand the definition of Long COVID to include organ damage or recognize COVID-19-induced organ damage as a distinct condition affecting many symptomatic and asymptomatic individuals after COVID-19 infections.It is important to consider that many known adverse health outcomes,including heart conditions and cancers,can be asymptomatic until harm thresholds are reached.Many more medical conditions can be identified by testing than those that are recognized through reported symptoms.It is therefore important to similarly recognize that while Long COVID symptoms are associated with organ damage,there are many individuals that have organ damage without displaying recognized symptoms and to include this harm in the characterization of COVID-19 and in the moni-toring of individuals after COVID-19 infections.
机标关键词：spectrumreviewdamagelongwithfromcoviddisease
论文发表日期：2025-02-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：10( 66-75 )
英文信息