半月板组织工程研究进展
陈松
符培亮
丛锐军
吴宇黎
1.第二军医大学附属上海长征医院关节外科,2000032.第二军医大学附属上海长征医院关节外科,2000033.第二军医大学附属上海长征医院关节外科,2000034.第二军医大学附属上海长征医院关节外科,200003
摘要：Objective To review the current research progress of meniscus tissue engineering. Methods Recent literatures concerning meniscus tissue engineering at home and abroad are extensively reviewed, and the current situation and progress are summarized. Results The research of meniscus tissue engineering mainly focuses on the selection of seed cells and their potential of differentiation into chondrocytes, the selection of scaffold materials and their mechanical properties, the mechanisms of action of cytokines in the process of cell culture, the effects of mechanical stimulation on cartilage differentiation and so on. Conclusions Many achievements have been obtained in meniscus tissue engineering. The next study focuses are to ifnd the seed cells more in accordance with the physiological process, easy to culture and with higher chondrogenic differentiation ability, to explore the cytokines that promote seed cells to differentiate into chondrocytes, especially fibrochondrocytes and their mechanisms of action in the process of differentiation, to look for the scaffold materials with strong morphological plasticity, no antigenicity, good degradability, and mechanical properties close to those of the scaffold materials of normal meniscuses.
机标关键词：组织工程半月板
分类号：R318(医用一般科学)R681.3(骨科学（运动系疾病、矫形外科学）)
资助基金：国家自然科学基金(81000798)
论文发表日期：2013-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：5( 694-698 )
英文信息