肿瘤型人工关节假体无菌性松动率及相关因素
肖何
牛晓辉
1.100035,北京积水潭医院骨肿瘤科2.100035,北京积水潭医院骨肿瘤科
摘要：With the development of chemotherapy, imaging, surgical techniques and material science, limb-salvage has become a widely accepted concept in the treatment of bone and soft tissue tumors. Prosthetic reconstruction after tumor segment resection has become a common operation method. In the history, there appeared many kinds of materials for the reconstruction after the resection of tumors. The megaprosthesis has a history of more than 60 years, and has become the mainstream now, with many advantages over the other reconstruction materials. The aseptic loosening of megaprotheses is a common postoperative complication and also a prominent cause of prosthesis failure. How high is the aseptic loosening rate? Will the rate be affected by such factors as the patient’s age, gender, disease category, implantation site, reconstruction length, chemotherapy and so on? Will the rate be obviously reduced due to the improvement of megaprotheses? These questions are worth researching. The aseptic loosening rate of megaprostheses and related factors are reviewed in this article based on previous studies. According to previous reports, many factors concerning the patient and the prosthesis have an impact on the aseptic loosening rate. The clear and deifnite related factors included the implantation site, porous coating in the collar, type of articulation, age at the time of surgery and reconstruction length, and the gender and disease category are irrelevant factors. As to the size of intramedullary stem, ifxation mode, modular/custom and chemotherapy, their correlation with the aseptic loosening rate is still unclear.
机标关键词：肿瘤型人工关节假体无菌性松动相关因素related factorspostoperative complicationprosthesis failure保肢治疗
分类号：R738.1(运动系肿瘤)
论文发表日期：2014-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：5( 365-369 )
英文信息