腰椎间盘营养扩散途径的DCE-MRI研究进展
陈春1
郭勇2
任爱军2
阮狄克1
1.海军总医院骨科,北京,1000482.海军总医院放射科
摘要：Intervertebral discs are the largest avascular structures in the body and depend entirely on the diffusion from blood vessels at the periphery for the supply of essential nutrients for cellular activity and the removal of metabolic wastes. Diffusion is the only source of nutrition to the intervertebral discs, and alteration of diffusion is considered to be the ifnal common pathway for disc degeneration. Yet diffusion remains poorly understood due to the paucity of reliable methods to study noninvasive diffusion in human beings in vivo. In recent years, Dynamic Contrast Enhanced-Magnetic Resonance Imaging ( DCE-MRI ) has emerged as a powerful and reliable tool to analyze the diffusion in lumbar discs. Endplate structures have also been proved to have the function of controlling the process of diffusion, and can be identified by DCE-MRI. This review focuses on the current knowledge, methodology, various factors inlfuencing the diffusion properties of the discs and the quantitative analysis of the normal, aging or degenerative intervertebral discs of this promising technique.
机标关键词：腰椎间盘扩散途径
分类号：R445.2,R681.5(诊断学)
资助基金：国家自然科学基金(81272044)
论文发表日期：2014-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：5( 630-634 )
英文信息