多学科协作积极开展膝关节周围骨肉瘤患者的保肢治疗
张春林
同济大学附属上海市第十人民医院骨科, 上海,200072
摘要：Osteosarcoma often occurs around the knee, especially in the distal femur and the proximal tibia. With the progress of chemotherapy and imaging technology and the promotion of limb salvage treatment, limb salvage procedure with neoadjuvant chemotherapy is the priority for the management of osteosarcoma around the knee. However, aseptic loosening of the prosthesis after replacement and lower limb discrepancy are 2 main difficulties in limb salvage for osteosarcoma around the knee. Moreover, for the patients with recurrence and metastasis, how to choose the optimal treatment is still challenging. The multidisciplinary team ( MDT ) consists of surgeons, radiologists, histopathologists, oncologists, clinical nurse specialists, allied health professionals, and multidisciplinary team coordinators. The MDT, as a new clinical model at present, plays a vital role in the diagnosis and treatment of osteosarcoma around the knee. It is helpful for developing the optimal treatment, choosing the reasonable surgical method and adjuvant therapy, improving the correct diagnosis and successful surgery rate, and reducing the misdiagnosis, surgery complication, recurrence and metastasis rate. We may expect a higher survival rate and better functional outcomes with a multidisciplinary approach.
关键词：骨肉瘤膝关节前导性化疗关节成形术置换膝保肢手术
分类号：R738.1(运动系肿瘤)R687.3(骨科学（运动系疾病、矫形外科学）)
资助基金：国家自然科学基金 (NSFC 81572630)
论文发表日期：2017-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：3( 401-403 )
英文信息