多发骨肉瘤的诊疗现状及起源问题初步探讨
张浩强1
鲁亚杰2
李明辉2
李旭升1
甄平1
王臻2
1.中国人民解放军联勤保障部队第九四○医院骨科中心关节外科, 730050 兰州2.空军军医大学西京医院骨肿瘤科,, 730050 兰州
摘要：To review the research and clinical status of multifocal osteosarcoma (MFOS), and discuss its origin.Osteosarcoma (OS) is one of the most common malignant bone tumors in adolescents, with metastasis in early stage and the five year survival is only about 60％.MFOS was reported by Silverman firstly in 1936, which was rare but invasive.There have been only 300 cases reported in literature till now.MFOS is characterized by the presence of tumor lesions in osseous sites without pulmonary metastasis.The MFOS patients present rapid progress, poor reaction with chemo-drugs and with a very terrible outcome.However, it has low incidence.With clinical and economic progress, the detection rate of MFOS has been promoted in recent years.Along with the development of novel research methods, deeper understanding makes the treatment much more individualized.
关键词：多发骨肉瘤流行病学诊断化疗基因测序综述
分类号：R738.1(运动系肿瘤)
论文发表日期：2019-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：4( 71-74 )
英文信息