股骨近端骨原发性假肌源性血管内皮瘤一例影像及病理分析
周兴顺1
过哲2
1.661600 云南省,中国人民解放军联勤保障部队第九二六医院放射科2.100035 北京,首都医科大学附属北京积水潭医院放射科
摘要：Pseudomyogenic hemangioendothelioma(PHE)is a rare intermediate vascular tumor originating from bone,which has been less reported in radiological studies.It was previously known as epithelioid sarcoma-like hemangioendothelioma(ES-HE).The tumor cells exhibit bright eosinophilic cytoplasm and morphologically resemble rhabdomyoblasts,while immunohistochemistry demonstrates endothelial differentiation.In the 2013 WHO classification of soft tissue and bone tumors,the term PHE was used.The tumor exhibits invasiveness,but metastasis is rare.It is classified as an intermediate vascular neoplasm.The 2020 classification maintains the same name and classification,and emphasizes the sensitivity of FOSB protein immunohistochemical staining in diagnosing PHE.Herein,we report the radiological findings of a surgically and pathologically confirmed case of primary bone PHE.In this case,the lesion was localized in the proximal femur and exhibited irregular lytic bone destruction with partial sclerotic borders.Residual bony trabeculae was visible internally,and consistent with the literature and characteristics of intermediate-type PHE with no periosteal reaction or cortical breakthrough.CT and MRI enhancement scans revealed significant enhancement in line with its vascular origin.MRI also showed minimal focal hemorrhagic signals,and the MRI low signal margin around the lesion extended wider than the CT sclerotic margin,which were consistent with the histological features of focal bleeding and iron-hemosiderin deposition.
关键词：血管内皮瘤股骨肿瘤骨肿瘤骨原发性假肌源性血管内皮瘤
分类号：R739.9(其他部位肿瘤)
论文发表日期：2024-08-19
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：3( 627-629 )
英文信息