未分化多形性肉瘤患者的个体化全股骨与膝关节人工假体置换一例报道
武圆圆
尚琦松
李哲
陆云
向伟
宋兴华
830000 乌鲁木齐,新疆医科大学第六附属医院脊柱外科/骨肿瘤科
摘要：Objective To summarize the etiological mechanism,clinical manifestations,pathological manifestations,diagnostic methods,differential diagnosis and treatment of undifferentiated pleomorphic sarcoma through clinical treatment and related literature analysis,and to provide treatment ideas for clinical diagnosis and treatment.Methods The diagnosis,clinical manifestations,differential diagnosis and treatment of a patient with undifferentiated pleomorphic sarcoma in our department were recorded,and relevant literature was screened and analyzed.Results The male patient was 47 years old,and was diagnosed as undifferentiated pleomorphic sarcoma through preoperative puncture biopsy.After clear diagnosis and evaluation of the patient's condition,one cycle of neoadjuvant chemotherapy was given to the patient,followed by resection of femur bone tumor supplemented with individualized total femur and knee artificial prosthesis replacement,and four cycles of neoadjuvant chemotherapy were given to the patient after surgery.The patient's incision recovered well without any other obvious discomfort.No dislocation or breakage of the prosthesis was seen.Moderate functional exercises were carried out,and the follow-up continued.Conclusions Undifferentiated pleomorphic sarcoma can be treated by artificial prosthesis replacement combined with neoadjuvant chemotherapy,which can control the recurrence and metastasis,helping the patient to recover well.
关键词：股骨肿瘤膝关节肉瘤假体植入关节成形术置换膝未分化多形性肉瘤
分类号：R738.1(运动系肿瘤)
资助基金：国家自然科学基金(82172454)
论文发表日期：2025-05-19
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：6( 446-451 )
英文信息