颈椎Modic改变的发生机制及治疗现状
陈双1
王开众1
李忠海2
1.116600 辽宁省,大连医科大学第一附属医院骨科,骨科疾病修复与重塑分子机制重点实验室2.116600 辽宁省,大连医科大学第一附属医院骨科,骨科疾病修复与重塑分子机制重点实验室;116600 辽宁省,大连干细胞与精准医学创新研究院
摘要：Neck pain is a clinical condition caused by a variety of factors,and its prevalence is on the rise as the world ages.Neck pain places a huge financial burden on society and individuals.Modic changes refer to abnormal signals in MRI of the endplate of the vertebral body and the tissues under the endplate.Different types of Modic changes have different histological characteristics.C5-6 segments are the most common,and cervical Modic change type Ⅰ is mostly correlated with cervical pain.There are some controversies about the cause of cervical Modic changes,but many studies have shown that the main pathogenic factors include disc degeneration,inflammation,infection,genetic mutation,etc.Neck pain due to Modic changes in the cervical spine has become an important factor causing disability,but there are fewer studies comparing low back pain due to Modic changes in the lumbar spine.This article summarizes the domestic and international studies on cervical Modic changes in recent years to provide references for clinical treatment of neck pain patients with cervical Modic changes.
关键词：颈痛脊柱疾病椎间盘退行性变Modic改变综述
分类号：R681.5(骨科学（运动系疾病、矫形外科学）)
论文发表日期：2025-07-19
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：5( 623-627 )
英文信息