Expression of synaptosomal-associated protein-25 in the rat brain after subarachnoid hemorrhage********
Gang Chen
Tong Hu
Qi Li
Jianke Li
Yang Jia
Zhong Wang
摘要：Synaptosomal-associated protein-25 is an important factor for synaptic functions and cognition. In this study, subarachnoid hemorrhage models with spatial learning disorder were established through a blood injection into the chiasmatic cistern. Immunohistochemical staining and western blot analysis results showed that synaptosomal-associated protein-25 expression in the temporal lobe, hippocampus, and cerebel um significantly lower at days 1 and 3 fol owing subarachnoid morrhage. Our findings indicate that synaptosomal-associated protein-25 expression was down-regulated in the rat brain after subarachnoid hemorrhage.
机标关键词：subarachnoid hemorrhagewestern blot analysisspatial learningtemporal lobe
资助基金：grants from the National Natural Science Foundation of China, (No.81171105,81271300, and 81100872)Jiangsu Provincial Outstanding Medical Academic Leader Program, (No. LJ201139)the National Key Technology Research &Development Program for the Twelfth Five-year Plan of China, (No.2011BAI08B05 and 2011BAI08B06)grants from Education Department of Jiangsu Province, (No.11KJB320011)a grant from Suzhou Government, (No. SYS201109)
论文发表日期：2013-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：10( 2693-2702 )
英文信息