Pre-moxibustion and moxibustion prevent Alzheimer’s disease***
Yanjun Du
Ruolan Liu
Guojie Sun
Peiyan Meng
Jie Song
摘要：The Alzheimer’s disease model in Wistar rats was established by injection of amyloid β-peptide (Aβ1-42 ) into the hippocampal CA1 region. Rats were treated with suspended moxibustion on Baihui (GV20) and Shenshu (BL23) acupoints. Prior to and post Aβ1-42 exposure. Results showed no evidence of apoptosis in hippocampal neurons, a significantly reduced apoptosis rate of neurons and improved learning and memory abilities were observed in the Alzheimer’s disease model. In particular, moxibustion prior to Aβ1-42 exposure was more effective than moxibustion after Aβ1-42 exposure in protecting the neuronal structure and lowering the apoptosis rate. Our findings indicate that a combination of preventive and therapeutic moxibustion has a beneficial effect for the tion of Alzheimer’s disease development.
机标关键词：disease modellearning and memoryhippocampal neuronsWistar rats
资助基金：the Natural Science Foundation of China, (No.30901925,81173323, and 81273864)
论文发表日期：2013-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：9( 2811-2819 )
英文信息