Monitoring somatosensory evoked potentials in spinal cord ischemia-reperfusion injury
Yiming Ji
Bin Meng
Chenxi Yuan
Huilin Yang
Jun Zou
摘要：It remains unclear whether spinal cord ischemia-reperfusion injury caused by ischemia and other non-mechanical factors can be monitored by somatosensory evoked potentials. Therefore, we monitored spinal cord ischemia-reperfusion injury in rabbits using somatosensory evoked potential detection technology. The results showed that the somatosensory evoked potential latency was significantly prolonged and the amplitude significantly reduced until it disappeared during the period of spinal cord ischemia. After reperfusion for 30-180 minutes, the amplitude and latency began to gradual y recover; at 360 minutes of reperfusion, the latency showed no significant difference compared with the pre-ischemic value, while the somatosensory evoked potential amplitude in-creased, and severe hindlimb motor dysfunctions were detected. Experimental findings suggest that changes in somatosensory evoked potential latency can reflect the degree of spinal cord ischemic injury, while the amplitude variations are indicators of the late spinal cord reperfusion injury, which provide evidence for the assessment of limb motor function and avoid iatrogenic spinal cord injury.
机标关键词：spinal cord ischemiaevoked potentialsreperfusion injuryspinal cord injurymotor function
资助基金：This study was supported by the National Natural Science Foundation of China, (No.81101370,81101399,81272018)the Natural Science Foundation of Jiangsu Province in China, (No. BK2011303)Jiangsu Province Science and Technology Support Program (Social Development) in China, (No. BE2011672)University Natural Science Research Foundation of Jiangsu Province for Higher Education, (No.12KJB320008)Col ege Graduate Research and Innovation Plan of Jiangsu Province in China, (No. CXZZ11_0126)
论文发表日期：2013-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：8( 3087-3094 )
英文信息