Critical illness polyneuropathy and myopathy:a systematic review
Chunkui Zhou
Limin Wu
Fengming Ni
Wei Ji
Jiang Wu
Hongliang Zhang
摘要：Critical illness polyneuropathy and critical illness myopathy are frequent complications of severe illness that involve sensorimotor axons and skeletal muscles, respectively. Clinically, they manifest as limb and respiratory muscle weakness. Critical illness polyneuropathy/myopathy in isolation or combination increases intensive care unit morbidity via the inability or dififculty in weaning these patients off mechanical ventilation. Many patients continue to suffer from decreased exercise capacity and compromised quality of life for months to years after the acute event. Substantial progress has been made lately in the understanding of the pathophysiology of critical illness polyneuropathy and myopathy. Clinical and ancillary test results should be carefully interpreted to differentiate critical illness polyneuropathy/myopathy from similar weaknesses in this patient population. The present review is aimed at providing the latest knowledge concerning the pathophysiology of critical illness polyneuropathy/myopathy along with relevant clinical, diagnostic, differentiating, and treatment information for this debilitat-ing neurological disease.
机标关键词：critical illnessmechanical ventilationintensive care unitexercise capacityskeletal musclesquality of lifetest results
资助基金：grants from China Scholarship Council, (No.2008102056)the National Natural Science Foundation of China, (No.81241147)
论文发表日期：2014-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：10( 101-110 )
英文信息