Targeted thrombolysis strategies for neuroprotective effect
Junping Zhang
Guoxing Ma
Zhimin Lv
Yu Zhou
Chunguang Wen
Yaqing Wu
Ruian Xu
摘要：Stroke is usually treated by systemic thrombolytic therapy if the patient presents within an ap-propriate time window. There is also widespread interest in the development of thrombolytic agents that can be used in cases of delayed presentation. Current agents that can be used in cases of delayed presentation of nerve damage by thrombus. Current systemic thrombolytic therapy is associated with adverse effects such as ifbrinogenolysis and bleeding. In an attempt to increase the efifcacy, safety, and speciifcity of thrombolytic therapy, a number of targeted thrombolytic agents have been studied in recent years. This review focuses on the concepts underlying targeted thrombolytic therapy and describes recent drug developments in this ifeld.
机标关键词：thrombolytic therapyused intime window
资助基金：This study was supported by the National Natural Science Foundation of China, (No.81271692)
论文发表日期：2014-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：7( 1316-1322 )
英文信息