Green tea polyphenols protect spinal cord neurons against hydrogen peroxide-induced oxidative stress
Jianbo Zhao
Shiqiang Fang
Yajiang Yuan
Zhanpeng Guo
Jinhao Zeng
Yue Guo
Peifu Tang
Xifan Mei
摘要：Green tea polyphenols are strong antioxidants and can reduce free radical damage. To investigate their neuroprotective potential, we induced oxidative damage in spinal cord neurons using hy-drogen peroxide, and applied different concentrations (50-200 μg/mL) of green tea polyphenol to the cell medium for 24 hours. Measurements of superoxide dismutase activity, malondial-dehyde content, and expression of apoptosis-related genes and proteins revealed that green tea polyphenol effectively alleviated oxidative stress. Our results indicate that green tea polyphenols play a protective role in spinal cord neurons under oxidative stress.
机标关键词：oxidative stressspinal cordgreen tea polyphenolssuperoxide dismutase activityfree radical damageoxidative damage
论文发表日期：2014-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：7( 1379-1385 )
英文信息