Transplantation of human amniotic epithelial cells repairs brachial plexus injury:pathological and biomechanical analyses
Qi Yang
Min Luo
Peng Li
Hai Jin
摘要：A brachial plexus injury model was established in rabbits by stretching the C6 nerve root. Imme-diately after the stretching, a suspension of human amniotic epithelial cells was injected into the injured brachial plexus. The results of tensile mechanical testing of the brachial plexus showed that the tensile elastic limit strain, elastic limit stress, maximum stress, and maximum strain of the injured brachial plexuses were signiifcantly increased at 24 weeks after the injection. The treat-ment clearly improved the pathological morphology of the injured brachial plexus nerve, as seen by hematoxylin eosin staining, and the functions of the rabbit forepaw were restored. These data indicate that the injection of human amniotic epithelial cells contributed to the repair of brachial plexus injury, and that this technique may transform into current clinical treatment strategies.
机标关键词：brachial plexusepithelial cellsmechanical testingclinical treatmentnerve root
资助基金：This study was financially supported by a grant from the Science and Technology Development Project of Jilin Province of China, (No.20110492)
论文发表日期：2014-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：5( 2159-2163 )
英文信息