The treatment of Parkinson’s disease with deep brain stimulation：current issues
Alexia-Sabine Moldovan
Stefan Jun Groiss
Saskia Elben
Martin Südmeyer
Alfons Schnitzler
Lars Wojtecki
摘要：Deep brain stimulation has become a well-established symptomatic treatment for Parkinson’s disease during the last 25 years. Besides improving motor symptoms and long-term motor com-plications, positive effects on patients’ mobility, activities of daily living, emotional well-being and health-related quality of life have been recognized. Apart from that, numerous clinical trials analyzed effects on non-motor symptoms and side effects of deep brain stimulation. Several technical issues and stimulation paradigms have been and are still being developed to optimize the therapeutic effects, minimize the side effects and facilitate handling. This review summarizes current therapeutic issues,i.e., patient and target selection, surgical procedure and programming paradigms. In addition it focuses on neuropsychological effects and side effects of deep brain stimulation.
机标关键词：deep brain stimulationside effectstherapeutic effectstarget selectionquality of lifeclinical trials
论文发表日期：2015-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：5( 1018-1022 )
英文信息