Enhancing endogenous stem cells in the newbornvia delayed umbilical cord clamping
Christopher Lawton
Sandra Acosta
Nate Watson
Chiara Gonzales-Portillo
hTeo Diamandis
Naoki Tajiri
Yuji Kaneko
Paul R. Sanberg
Cesar V. Borlongan
摘要：There is currently no consensus among clinicians and scientists over the appropriate or optimal timing for umbilical cord clamping. However, many clinical studies have suggested that delayed cord clamping is associated with various neonatal beneifts including increased blood volume, reduced need for blood transfusion, increased cerebral oxygenation in pre-term infants, and decreased frequency of iron deifciency anemia in term infants. Human umbilical cord blood con-tains signiifcant amounts of stem and progenitor cells and is currently used in the treatment of several life-threatening diseases. We propose that delayed cord clamping be encouraged as it en-hances blood lfow from the placenta to the neonate, which is accompanied by an increase supply of valuable stem and progenitor cells, as well as may improve blood oxygenation and increase blood volume, altogether reducing the infant’s susceptibility to both neonatal and age-related diseases.
机标关键词：progenitor cellsblood volumeumbilical cord bloodcerebral oxygenationblood transfusionused in
论文发表日期：2015-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：4( 1359-1362 )
英文信息