Regulation of axonal remodeling following spinal cord injury
Anne Jacobi
Florence M.Bareyre
摘要：Central nervous system injuries,such as spinal cord injury (SCI),are a leading cause of disability in young adults.SCIs generally have severe clinical consequences and often lead to loss of motor or sensory input below the segment of injury.While complete injuries generally show very little improvement over time,functional recovery can be seen following partial injuries.A number of studies over the last decade have aimed to identify the anatomical basis of this recovery process.They showed that while long-distance axonal regeneration is restricted in the mammalian central nervous system (CNS),supraspinal and intraspinal CNS axons can remodel after injury (Weidner et al.,2001;Bareyre et al.,2004;Girgis et al.,2007;van den Brand et al.,2012;Z(o)rner et al.,2014).
机标关键词：central nervous systemaxonal regenerationspinal cord injuryyoung adults
资助基金：Work in FMB laboratory is supported by grants from the Deutsche Forschungsgemeinschaft(DFG)Work in FMB laboratory is supported by grants from the Deutsche Forschungsgemeinschaft( SFB870)by the Munich Center for System Neurology(SyNergy)by the Munich Center for System Neurology( EXC1010)
论文发表日期：2015-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：3( 1555-1557 )
英文信息