Superparamagnetic iron oxide nanoparticles: promote neuronal regenerative capacity?
Jenni Neubert
Anja U.Br(a)uer
摘要：Currently,we know that neuronal outgrowth during development and regeneration requires a complex interaction of intra-and extracellular molecules such as growth factors,neurotransmitters and extracellular matrix proteins (O'Donnell et al.,2009).Furthermore,the discovery of a broad spectrum of growth-promoting cues has led to novel concepts for therapeutic strategies.However,although our understanding of the molecular mechanisms underlying neuronal regeneration is constantly growing,there is still no therapy for the treatment of brain or spinal cord injuries (SCI) (Filli and Schwab,2012).Recent attempts have been made to influence regeneration using nano-scaled particles that specifically act at the molecular level (Polak and Shefi,2015).
机标关键词：spinal cord injuriesmolecular mechanismsextracellular matrixgrowth factors
论文发表日期：2015-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 1568-1569 )
英文信息