Cognitive training in neurodegenerative diseases: a way to boost neuroprotective molecules?
Francesco Angelucci
Carlo Caltagirone
Alberto Costa
摘要：Neurotrophins,and growth factors in general,are proteins which exert many actions in central nervous system neurons.Neurotrophins promote the survival and neuronal function of neurons and exert neuroprotective effects in pathological models of neurodegenerative diseases.In humans several clinical trials based on the use of these proteins have been carried out.Among them,it is worth to mention gene therapy especially in Parkinson's disease (PD) (Kordower and Bjorklund,2013),and a series of experiments using vectors capable of carrying neurotrophins in the selected target region where they can exert their beneficial action (Ghosh et al.,2014).
机标关键词：neurodegenerative diseasesneuroprotective effectscentral nervous systemclinical trialsgrowth factorstarget regiongene therapy
论文发表日期：2015-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 1754-1755 )
英文信息