Purinergic signalling in neuroregeneration
Geoffrey Burnstock
摘要：Purinergic signalling,adenosine 5'-triphosphate (ATP) as an extracellular signalling molecule,was proposed in 1972 (Burnstock,1972).However,it was not generally accepted until the early 1990s when receptors for ATP and its breakdown product adenosine were cloned and characterised (Ralevic and Burnstock,1998).Four P1 (adenosine) receptors are recognised (A1,A2A,A2B and A3),seven P2X ion channel receptors (P2X1-7) and eight P2Y G protein-coupled receptors (P2Y1,P2Y2,P2Y4,P2Y6,P2Yu,P2Y12,P2Y13,P2Y14).The purinergic signalling field is now widely accepted and expanding in many different directions (Burnstock,2012).
机标关键词：ion channel
论文发表日期：2015-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：1( 1919 )
英文信息