Pharmacological inhibition of cation-chloride cotransporters for neurological diseases
Rachel Nepomuceno
Dandan Sun
摘要：γ-Aminobutyric acid (GABA) is a major neurotransmitter and plays important roles in both the developing and mature central nervous system (CNS).One way that GABA can act is by binding to fast,ionotropic GABAA receptors in neurons.The binding of GABA to GABAA receptors causes a conformational change that opens ion channels,allowing the passage of Cl-ions.
机标关键词：central nervous systemconformational changeion channels
论文发表日期：2015-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 1924-1925 )
英文信息