Perspectives on the role of Pannexin 1 in neural precursor cell biology
Juan C Sanchez-Arias
Leigh E Wicki-Stordeur
Leigh Anne Swayne
摘要：We recently reported that targeted deletion of Pannexin 1 in neural precursor cells of the ventricular zone impairs the maintenance of these cells in healthy and stroke-injured brain. Here we frame this exciting new ifnding in the context of our previous studies on Pannexin 1 in neural precursors as well as the close rela-tionship between Pannexin 1 and purinergic receptors established by other groups. Moreover, we identify important gaps in our understanding of Pannexin 1 in neural precursor cell biology in terms of the under-lying molecular mechanisms and functional/behavioural outcomes.
机标关键词：neural precursor cellmolecular mechanisms
资助基金：the Canadian Institutes of Health Research(CIHR Grant MOP142215)
论文发表日期：2016-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：5( 1540-1544 )
英文信息