Regulation of neural stem/progenitor cell functions by P2X and P2Y receptors
Peter Illes
Patrizia Rubini
摘要：Neural stem/progenitor cells: Radial glial cells constitute mul-tipotent cells in the ventricular zone, lining the wall of the lat-eral ventricle of the embryonic brain. They have the capacity to give rise to cells belonging to all three major linages (neu-rons, astrocytes and oligodendrocytes) of the nervous system (Tang and Illes, 2017). Contrary to the long-held dogma, persistent neurogenesis throughout life occurs in two specific neurogenic niches of the adult brain: the subventricular zone (SVZ) of the lateral ventricle and the subgranular zone (SGZ) of the hippocampal dentate gyrus (Illes et al., 2013). Although there is no general consensus on terminology, we will call the embryonic radial glia and its progeny "neural stem cells"(NSCs) and their adult counterparts "neural progenitor cells"(NPCs).
机标关键词：progenitor cellssubventricular zonelateral ventriclenervous systemdentate gyrusstem cells
资助基金：Deutsche Forschungsgemeinschaft(DFG)Deutsche Forschungsgemeinschaft( IL 20/21-1)Sino-German Centre(GZ919)
论文发表日期：2017-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 395-396 )