The reasons for end-to-side coaptation: how does lateral axon sprouting work?
Stefano Geuna
Igor Papalia
Giulia Ronchi
Francesco Stagno d'Alcontres
Konstantinos Natsis
Nikolaos A. Papadopulos
Michele R. Colonna
摘要:Nerve fibers are attracted by sutureless end-to-side nerve coaptation into the recipient nerve. Opening a window in the epineurium enhances axon attraction and myelination. The authors analyze the features of nerve repair by end-to-side coaptation. They highlight the known mechanisms of axon sprouting and different hypotheses of start up signals (presence or absence of an epineurial window, role of Schwann cells, signaling from the distal trunk). The clinical literature is also presented and differences between experimental and clinical applications are pointed out. The authors propose their point of view and perspectives deriving from recent experimental and clinical experiences.
机标关键词:Schwann cellsnerve repairstart up
论文发表日期:2017-01-01
在线出版日期:2025-08-15(本平台首次上网日期,不代表文献的发表时间)
页数:5( 529-533 )
英文信息
