Design and criteria of electrospun fibrous scaffolds for the treatment of spinal cord injury
Barbara Vigani
Silvia Rossi
Giuseppina Sandri
Maria Cristina Bonferoni
Franca Ferrari
摘要:The complex pathophysiology of spinal cord injury may explain the current lack of an effective therapeutic approach for the regeneration of damaged neuronal cells and the recovery of motor functions.Many efforts have been performed to design and develop suitable scaffolds for spinal cord regeneration,keeping in mind that the reconstruction of a pro-regenerative environment is the key challenge for an effective neurogenesis.The aim of this review is to outline the main features of an ideal scaffold,based on biomaterials,produced by the electrospinning technique and intended for the spinal cord regeneration.An overview of the polymers more investigated in the production of neural fibrous scaffolds is also provided.
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论文发表日期:2017-01-01
在线出版日期:2025-08-15(本平台首次上网日期,不代表文献的发表时间)
页数:5( 1786-1790 )
英文信息
