Promoting functional recovery by inhibition of repulsive guidance molecule-a after spinal cord injury
Hiroshi Nakagawa
Masahiko Takada
摘要：Spinal cord injury (SCI) leads to permanent disability with motor and sensory dysfunctions.The mature mammalian central nervous system (CNS) possesses a limited capacity to regenerate/regrow after injury.Research works on functional restoration from SCI via enhanced sprouting of injured/spared fibers based on molecular mechanisms have greatly increased in recent years,especially using small animal models such as anamniotes and rodents.These results allow us to understand the advanced mechanisms of axonal remodeling after SCI.However,for a successful translation of the mechanisms into human patients with SCI,we have to consider certain anatomical and physiological differences in neural circuits between small animals and humans.
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论文发表日期：2018-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 981-982 )