Neuroplasticity, limbic neuroblastosis and neuro-regenerative disorders
Mahesh Kandasamy
Ludwig Aigner
摘要：The brain is a dynamic organ of the biological renaissance due to the existence of neuroplasticity.Adult neurogenesis abides by every aspect of neuroplasticity in the intact brain and contributes to neural regeneration in response to brain diseases and injury.The occurrence of adult neurogenesis has unequivocally been witnessed in human subjects,experimental and wildlife research including rodents,bats and cetaceans.Adult neurogenesis is a complex cellular process,in which generation of neuroblasts namely,neuroblastosis appears to be an integral process that occur in the limbic system and basal ganglia in addition to the canonical neurogenic niches.Neuroblastosis can be regulated by various factors and contributes to different functions of the brain.The characteristics and fate of neuroblasts have been found to be different among mammals regardless of their cognitive functions.Recently,regulation of neuroblastosis has been proposed for the sensorimotor interface and regenerative neuroplasticity of the adult brain.Hence,the understanding of adult neurogenesis at the functional level of neuroblasts requires a great scientific attention.Therefore,this mini-review provides a glimpse into the conceptual development of neuroplasticity,discusses the possible role of different types of neuroblasts and signifies neuroregenerative failure as a potential cause of dementia.
机标关键词：
资助基金：the FWF Special Research Program (SFB) F44 (F4413-B23)"Cell Signaling in Chronic CNS Disorders',and through funding from the European Union's Seventh Framework Program (FP7/2007-2013)a research grant from DST-SERB,New Delhi,India (EEQ/2016/000639)an Early Career Research Award (ECR/2016/000741)
论文发表日期：2018-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：5( 1322-1326 )
英文信息