Current surgical treatments for Parkinson's disease and potential therapeutic targets
Darrin J.Lee
Robert F.Dallapiazza
Philippe De Vloo
Andres M.Lozano
摘要：Currently,the most common surgical treatment for Parkinson's disease is deep brain stimulation (DBS).This treatment strategy is typically reserved for bradykinesia,rigidity and tremor in patients who no longer respond to medication in a predictable manner or who suffer medication-induced dyskinesias.In addition to DBS,ablative procedures like radiofrequency,radiosurgery and focused ultrasound are also utilized for select tremor symptoms.In this review,we discuss evolving surgical techniques,targets,and emerging technology.In addition,we evaluate potential paradigm shifts in treatment,including gene therapy,immunotherapy and cell transplantation.While these new techniques and treatment options are still in their infancy,advances in Parkinson's disease treatment are rapidly expanding.
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论文发表日期：2018-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：4( 1342-1345 )
英文信息