Cholinergic receptor, nicotinic, alpha 7 as a target molecule of Arctic mutant amyloid β
Naoya Sawamura
Ye Ju
Toru Asahi
摘要:Alzheimer's disease (AD) is a progressive cognitive disorder that develops predominantly in elderly patients and is characterized by cognitive impairments affecting memory,learning,and attention (Selkoe,2002).As the prevalence of AD is increasing concurrently with an increase in the aging demographic of society,the elucidation of its cause and underlying developmental mechanisms,as well as the development of preventive and therapeutic methods are eagerly awaited.Pathological features of AD include the appearance of senile plaques and neurofibrillary tangles throughout the cerebral cortex.
机标关键词:
论文发表日期:2018-01-01
在线出版日期:2025-08-15(本平台首次上网日期,不代表文献的发表时间)
页数:2( 1360-1361 )
