Use of longitudinal magnetic resonance imaging in preclinical models of spinal cord injury
Harun Najib Noristani
Florence Evelyne Perrin
摘要：Spinal cord injury (SCI) is a distressing event with grave so-cio/economic consequences to our society. Pathophysiologi-cal response following SCI involves blood-spinal cord barrier breakdown, neuroinflammation and formation of a glial scar that altogether govern the feasibility of spontaneous axonal re-growth and limited functional recovery. Great advances in understanding SCI pathophysiology have been achieved us-ing numerous transgenic mouse lines developed in different strains. However, there are inherent strain differences that affect inflammation, gliosis, axon regeneration and ultimately functional recovery after SCI.
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论文发表日期：2019-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 771-772 )