Sympathetic stimulation with norepinephrine may come at a cost
Lakshini Y. Herat
Markus P. Schlaich
Vance B. Matthews
摘要：Norepinephrine (NE;also known as noradrenaline) is the body's primary adrenergic neurotransmitter which belongs to the catecholamine family. Norepinephrine has pharmacologic effects on the α1 (Suita et al., 2015), α2 (Schwartz, 1997), β1, β2 and β3 (Tsukada et al., 2003) adrenoceptors. In the brain, norepinephrine increases arousal and alertness, promotes vigilance, enhances formation and retrieval of memory, and focuses attention. It also increases restlessness and anxiety. In the remainder of the body, norepinephrine increases heart rate and blood pressure, triggers the release of glucose from energy stores, increases blood ?ow to skeletal muscle and increases muscle contraction, reduces blood ?ow to the gastrointestinal system and its motility and lastly, inhibits voiding of the bladder (Goldstein, 2010). This last point is particularly interesting in the context of this perspective piece.
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论文发表日期：2019-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 977-978 )