Neurological functional evaluation based on accurate motions in big animals with traumatic brain injury
Ji-Peng Jiang
Xue-Gang Niu
Chen Dai
Ke Ma
Hui-You Xu
Shi-Xiang Cheng
Zhi-Wen Zhang
Feng Duan
Xu Zhu
Yu-Ting Wang
Xu-Yi Chen
Sai Zhang
摘要：An accurate and effective neurological evaluation is indispensable in the treatment and rehabilitation of traumatic brain injury. However, most of the existing evaluation methods in basic research and clinical practice are not objective or intuitive for assessing the neurological function of big animals, and are also difficult to use to qualify the extent of damage and recovery. In the present study, we established a big animal model of traumatic brain injury by impacting the cortical motor region of beagles. At 2 weeks after successful modeling, we detected neurological deficiencies in the animal model using a series of techniques, including three-dimensional motion capture, electromyogram and ground reaction force. These novel technologies may play an increasingly important role in the field of traumatic brain injury diagnosis and rehabilitation in the future. The experimental protocol was approved by the Animal Care and Use Committee of Logistics University of People's Armed Police Force (approval No. 2017-0006.2).
机标关键词：
资助基金：the National Natural Science Foundation of China, (No. 11672332, 11102235 and 31200809)the National Key Research and Development Plan of China, (No. 2016YFC1101500)the Science and Technology Program of Tianjin, China, (No. 17YFZCSY00620 and 16ZXHLSY00120)
论文发表日期：2019-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：6( 991-996 )
英文信息