Fine-tuning the response of growth cones to guidance cues: a perspective on the role of microRNAs
Sarah E. Walker
Gaynor E. Spencer
Robert L. Carlone
摘要：In the development and regeneration of the nervous system, neurons face the complex task of establishing and/or repairing neuronal con-nections and contacts. The formation of these neuronal circuits is largely coordinated by tightly regulated temporal and spatial changes in mRNA translation, which enables incredibly precise control over protein expression and localization (Jung and Holt, 2011). Local mRNA translation in specific cellular compartments appears to play a role in many processes that are important to nervous system development and regeneration, including: cell survival, migration, growth cone guidance, and synaptogenesis (Jung and Holt, 2011).
机标关键词：
资助基金：grants from the Natural Sciences and Engineering Research Council of Canada (2015-03780)grants from the Natural Sciences and Engineering Research Council of Canada ( to GES)grants from the Natural Sciences and Engineering Research Council of Canada ( and 2017-00008)grants from the Natural Sciences and Engineering Research Council of Canada ( to RLC)
论文发表日期：2019-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 1719-1720 )